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World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Nurse, Issue 220 - in French: Ecola Nationale de Sante Publique, Niamey

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Book Id: WPLBN0000191984
Format Type: PDF eBook
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Reproduction Date: 2005

Title: World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Nurse, Issue 220 - in French: Ecola Nationale de Sante Publique, Niamey  
Author: World Health Organization
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
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Publisher: World Health Organization

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Organization, W. H. (n.d.). World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Nurse, Issue 220 - in French. Retrieved from http://cn.ebooklibrary.org/


Description
Medical Reference Publication

Excerpt
I N T R O D U C T I O N The Thirteenth European Symposium on C l i n i c a l Pharmacological Evaluation kn Drug Control devoted t o Drugs i n Pregnancy and Delivery was held i n Schlangenbad, Federal Republic of Germany from 30 October to 2 November 1984. It was attended by 29 p a r t i c i p a n t s from 29 c o u n t r i e s , 17 temporary a d v i s e r s , 6 observers and 5 representatives from other o r g a n i z a t i o n s . D r M,N.G, Dukes, Regional O f f i c e r f o r Pharmaceuticals and Drug U t i l i z a t i o n at the WHO Regional Office f o r Europe, declared t h a t t h i s w a s a Symposium of which !+NO had high e x p e c t a t i o n s . It was now a q u a r t e r of a century since thalidomide came i n t o use; the tragedy a s s o c i a t e d with it had sparked a chain of events which s t i l l continued. After twenty-five years it was time to look back i n order b e t t e r t o look forward, The c e n t r a l l e s s o n o f thalidomide was t h a t we had t o prevent drugs doing harm i n pregnancy. Beyond t h a t , however, the Lesson should have c a r r i e d us i n two d i r e c t i o n s . On the one hand, s o c i e t y should have found ways of p r o t e c t i n g the s t a t e of pregnancy and the l i f e of the unborn c h i l d a g a i n s t unintended harm. On the Other hand, it should have found ways t o prevent drugs causing unnecessary i n j u r y of any nature. I f we had dared t o be sure t h a t both t h o s e l e s s o n s - which i n t e r s e c t e d a t the point of drugs in pregnancy - had been l e a r n e d , i n the sense t h a t we had found both t h e t e c h n i c a l and s o c i a l s o l u t i o n s t o these problems and rhe w i l l t o apply them, then the present meeting would not have been needed. Unhappily, we did not seem t o be a t a l l sure. In the twenty-five years since thalidomide, unborn c h i l d r e n had continued t o be i n j u r e d and drugs had pone on doing harm which had somerimes been d i s p r o p o r t i o n a t e t o t h e i r value. Neither r e g u l a t i o n nor s e l f - d i s c i p l i n e nor a combination of t h e two seemed t o have put things r i g h t . Sometimes the w i l l seemed t o f a i l , and sometimes the means. The r e g u l a t o r y s u p e r s t r u c t u r e t h a t had been e r e c t e d around drug s a f e t y sometimes seemed to the o u t s i d e r t o function l i k e a mindless bureacracy, impeding progress and s h u t t i n g one s t a b l e door a f t e r another a f t e r the horse had gone. Doctors, the pharmaceutical i n d u s t r y , drug r e g u l a t o r s and consumers had a l l done something of value, but it had not been enough. This meeting must p o i n t t h e way t o b e t t e r achievements.

Table of Contents
CONTENTS LIST OF CONTENTS FRANZ GROSS 1913-1984 1 INTRODUCTION 2 1. . GENERAL PROBLEMS OF DRUE TREATMENT IN PREGNANCY 3 2. SPECIFIC PROBLEMS I N THERAPY 5 2.1. DRUG TMATMENT OF PREGNANCY-INDUCED DISEASE 2.2. TREATMENT OF PRE-EXISTENT DISORDERS I N PREGNANCY 2.3. USE OF PSYCHOTROPIC DRUGS IN PREGNANCY 2.4. DRUG TREARlENT RELATING TO DELIVERY 3. DETECTION OF DRUG RISKS IN PREGNANCY 12 3.1. GENERAZ, 3.2. RELEVANCE OF ANIMAL STUDIES 3.3. USE OF CLINICAL DATA 4. INFORMATION TO HEALTH PKOFESSIONALS AND THE PUBLIC 16 5. CONSULTATION SERVICES ON THE USE OF DRUGS I N PREGNANCY 6. CONCLUSIONS 7. SUMMARY OF PRINCIPAL RECOMMENDATIONS 7a. ZUSMNFASSUNG DER WICHTIGSTEN EMPFEHLUNGEN SELECTED LITERATURE APPENDICES A THE CURRENT PATTERN OF DRUG USE IN PREGNANCY B LESSONS TO BE LEARNED FROM TNALILDOMIDE C DES: THE TIME-BOMB DRUE LIST OF PARTICIPANTS

 
 



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