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World Health Organization : Technical Report Series, No. 474: Pesticide Residues in Food

By D. C. Abbott

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Book Id: WPLBN0000131726
Format Type: PDF eBook
File Size: 1.5 MB
Reproduction Date: 2005
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Title: World Health Organization : Technical Report Series, No. 474: Pesticide Residues in Food  
Author: D. C. Abbott
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Abbott, D. C. (n.d.). World Health Organization : Technical Report Series, No. 474. Retrieved from http://cn.ebooklibrary.org/


Description
Medical Reference Publication

Excerpt
INTRODUCTION This annual Joint Meeting was held in pursuance of the recommendation made in 1961, at a meeting of a MiHO Expert Comnittee on Pesticide Residues held jointly with the FA0 Panel of Experts on the Use of Pesticides in Agriculture (WHO/FAO, 1962)> that studies be undertaken to evaluate possible hazards to man arising from the occurrence of residues of pesticides in foods. Following this recommendation, Joint Meetings of the FA0 Committee on Pesticides in Agriculture and the JVHO Expert Committee on Pesticide Residues were held in 1963 and 1965. The reports of these meetings (FAO/WHO, 1964 ; FA0,hIiH02 1965a), which were concerned primarily with establishing acceptable daily intakes (ADIs), and the supporting documents (FAO/WHO, 1965b, 196%) were then considered by the FA0 Working Party on Pesticide Residues with a view to recommending tolerances and appropriate methods of analysis for certain pesticides used on cereals (FAO, 1966). Joint Meetings of the FA0 Working Party of Experts on Pesticide Residues and the WHO Expert Committee on Pesticide Residues (referred to hereafter as Joint Meetings) were held in 1966, 1967, 1968, and 1969.

Table of Contents
CONTENTS Page 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2 . General considerations . . . . . . . . . . . . . . . . . . . . . . . . 6 2.1 Principles adopted . . . . . . . . . . . . . . . . . . . . . . . . 6 2.2 Value of a multidisciplinary approach . . . . . . . . . . . . . . . 7 2.3 Need for undertaking further work . . . . . . . . . . . . . . . . 7 2.4 Nature and availability of data considered . . . . . . . . . . . . . 7 2.5 Etiology and pathogenesis of l i ~ e rru mours in mice . . . . . . . . 8 2.6 Use of biochemical parameters for establishment of no-toxic-effect level'' 8 2.7 Possible interaction between pesticides . . . . . . . . . . . . . . . 9 2.8 Accidental poisoning and human toliicological data . . . . . . . . . 9 2.9 Possible contamination arising from the use of pesticides in the home, restaurants, and similar places . . . . . . . . . . . . . . . . . . 10 2.10 Classification of foods and definition of food groups . . . . . . . . 10 2.11 Recommendations for temporary tolerances . . . . . . . . . . . . 10 2.12 Methods of analysis . . . . . . . . . . . . . . . . . . . . . . . 11 2.13 Tolerances to be expressed to one sienificant digit . . . . . . . . . . . 11 2.14 DDT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.15 Expression of tolerances for fat-soluble pesticides in meat, milk, and fish 12 3 . Comparison of estimated intakes of pesticide residues and acceptable daily intakes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 3.1 Potential intakes of pesticide residues . . . . . . . . . . . . . . . 13 3.2 Consideration of results of total diet studies . . . . . . . . . . . . 14 4 . Evaluation of data for acceptable daily intakes . . . . . . . . . . . . . 15 4.1 Organochlorine insecticides . . . . . . . . . . . . . . . . . . . . 15 4.2 Herbicides and plant growth regulators . . . . . . . . . . . . . . 15 4.3 Organotin pesticides . . . . . . . . . . . . . . . . . . . . . . . 16 4.4 Organophosphorus and carbamate insecticides . . . . . . . . . . . 16 4.5 Miscellaneous pesticides . . . . . . . . . . . . . . . . . . . . . 17 5 . Evaluation of data for tolerances and practical residue limits . . . . . . . 17 5.1 Matters referred to the Joint hleering by the Codex Committee on Pesticide Residues . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 5.2 Pesticides reviewed in the light of new information . . . . . . . . . 18 5.3 Pesticides not previously considered for tolerances or practical residue limits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 6 . Future work . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 7 . Recommendations . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 7.1 Recommendations to FA0 and WHO . . . . . . . . . . . . . . . 20 7.2 General recommendations . . . . . . . . . . . . . . . . . . . . 20

 
 



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